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If someone has a folate deficiency and their B12 is suboptimal, thats when I might consider this. It also contains Betaine (Trimethylglycine), which supports liver function, including detoxification pathways, according to the brand

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Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

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