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In contrast, a prior history of ischemic stroke, chronic kidney disease (stage 3 and above), and atrial fibrillation was noted more in the GLP-1RA group
None of these signs are definitive on their own
Any oral tirzepatide product designed to be swallowed, rather than absorbed sublingually, would need bioavailability-enhancing technology similar to or better than the SNAC system used in oral semaglutide
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