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For the reaction considered above of NADH oxidation by oxygen, the maximal associated free energy that can be extracted is thus G = n x F x E = 2 x 100 kJ/(molxV) x (0.82-(-0.32)) V = 230 kJ/mol 90 k B T, where n=2 and F100kJ/mol/V
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Further, GSH depletion can inhibit DNA repair in bladder carcinoma cell lines after cisplatin or doxorubicin damage
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